INPUT will strive to make the control of complex upper limb prostheses simple, natural and to be used on a daily basis by amputees effortlessly after donning -"don and play". In INPUT, the main goal will be to transfer the obtained results from laboratory settings further towards a clinically and commercially viable medical product. Reliable, easy to apply, cost-effective signal acquisition Reliable, powerful real-time signal processing Quantifying true patient benefit Optimized end-user training Iterative clinical tests throughout the entire project The project builds on achievements reached in the EU FP7 IAPP projects AMYO (Grant No. 251555, 2011-2014) and MYOSENS (Grant No. 286208, 2012-2015), which were targeting improved signal acquisition and signal processing for advanced upper limb prosthetic control. In order to keep a realistic focus, the project will rely on well-known principles of advanced prosthesis control. Existing upper limb prosthetic hardware will be reused to minimize development time and costs. Improved electronics, algorithms and training will be the main innovations. INPUT will build on frequent end-user testing with amputees throughout the entire project. These will ensure targeted prototype development and market viability for advancing the technology from laboratory conditions to a high technology readiness level (TRL) of 8. ...